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  • 產品名稱:TIRAP抗原(重組蛋白

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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TIRAP抗原(重組蛋白)將進一步加強人才培養(yǎng)、產品**,持續(xù)不斷地提升企業(yè)核心竟爭力,實現(xiàn)具有高科技產業(yè)體系、知識化創(chuàng)業(yè)團隊的國際化企業(yè),更好、更快捷、更全方位的服務于生命科學領域,迎接新一輪世界經濟一體化所帶來的機遇與挑戰(zhàn)。
詳情介紹:

中文名稱: TIRAP抗原(重組蛋白)

英文名稱: TIRAP Antigen (Recombinant Protein)

別     名:  Mal; wyatt; BACTS1; MyD88-2

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Full length fusion protein

技術規(guī)格

Full name:

toll-interleukin 1 receptor (TIR) domain containing adaptor protein

Synonyms:

Mal; wyatt; BACTS1; MyD88-2

Swissprot:

P58753

Gene Accession:

BC032474

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.





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