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  • 產(chǎn)品名稱：TPPP抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
TPPP抗原（重組蛋白）將進(jìn)一步加強(qiáng)人才培養(yǎng)、產(chǎn)品**，持續(xù)不斷地提升企業(yè)核心竟?fàn)幜Γ瑢?shí)現(xiàn)具有高科技產(chǎn)業(yè)體系、知識(shí)化創(chuàng)業(yè)團(tuán)隊(duì)的國(guó)際化企業(yè)，更好、更快捷、更全方位的服務(wù)于生命科學(xué)領(lǐng)域，迎接新一輪世界經(jīng)濟(jì)一體化所帶來(lái)的機(jī)遇與挑戰(zhàn)。
詳情介紹：

中文名稱： TPPP抗原（重組蛋白）

英文名稱： TPPP Antigen (Recombinant Protein)

別     名：  p24; p25; TPPP1; TPPP/p25; p25alpha

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

tubulin polymerization promoting protein

Synonyms:

p24; p25; TPPP1; TPPP/p25; p25alpha

Swissprot:

O94811

Gene Accession:

BC131506

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.





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