概 述
Full name: |
cyclic nucleotide gated channel alpha 2 |
Synonyms: |
CNCA, CNG2, CNCA1, OCNC1, OCNCa, OCNCALPHA |
Swissprot: |
Q16280 |
Gene Accession: |
BC126302 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. |
