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  • 產(chǎn)品名稱：DOK3抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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我司的DOK3抗原（重組蛋白）受到了廣大科研單位的一致肯定和認(rèn)同，產(chǎn)品有保證，價(jià)格公道，傾力為國(guó)內(nèi)外科研院校實(shí)驗(yàn)室提供*上等的產(chǎn)品。若有需要，我司將竭誠(chéng)為您服務(wù)，歡迎廣大用戶來(lái)電來(lái)涵購(gòu)買！當(dāng)天生產(chǎn)，發(fā)貨及時(shí)，國(guó)內(nèi)包郵。
詳情介紹：


中文名稱： DOK3抗原（重組蛋白）

英文名稱： DOK3 Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to C terminal 300 amino acids of human DOK3

技術(shù)規(guī)格

Full name:

docking protein 3

Synonyms:

DOKL

Swissprot:

Q7L591

Gene Accession:

BC004564

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function





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