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  • 產(chǎn)品名稱:DUSP8 抗原

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:350
  • 產(chǎn)品庫存:35
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詳情介紹:



中文名稱: DUSP8 抗原 

英文名稱: DUSP8 Antigen

別    名:   HB5, HVH8, HVH-5, C11orf81

相關(guān)類別: 抗原

儲    存:   冷凍(-20℃)

概    述

Synthetic peptide corresponding to a region derived from 2-14 amino acids of human dual specificity phosphatase 8

技術(shù)規(guī)格

Full name:

dual specificity phosphatase 8

Synonyms:

HB5, HVH8, HVH-5, C11orf81

Gene Accession:

NP_004411

SwissProt:

Q13202

Background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the ***** brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.





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