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  • 產(chǎn)品名稱:KIF1C 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
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中文名稱: KIF1C 抗原(重組蛋白)

英文名稱: KIF1C Antigen (Recombinant Protein)

別     名:  kinesin family member 1C; SAX2; LTXS1; SATX2; SPAX2; SPG58

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概      述

Fusion protein corresponding to a region derived from 360-460 amino acids of human KIF1C

技術(shù)規(guī)格

Full name:

kinesin family member 1C

Synonyms:

SAX2; LTXS1; SATX2; SPAX2; SPG58

Swissprot:

O43896

Gene Accession:

BC034993

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis . KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons . Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle . Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta . In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.





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