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  • 產品名稱:OPTN 抗原(重組蛋白)

  • 產品型號:100ug
  • 產品廠商:通蔚生物
  • 產品價格:800
  • 產品庫存:35
  • 產品文檔:
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詳情介紹:


中文名稱: OPTN 抗原(重組蛋白)

英文名稱: OPTN Antigen (Recombinant Protein)

別     名:  optineurin; NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Fusion protein corresponding to C terminal 166 amino acids of human OPTN

技術規(guī)格

Full name:

optineurin

Synonyms:

NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

Swissprot:

Q96CV9

Gene Accession:

BC013876

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and *****-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.





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