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  • 產(chǎn)品名稱：兔抗RRP8多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫(kù)存：60
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
我司對(duì)那些奮斗在科學(xué)領(lǐng)域的工作者表示衷心的感謝和祝愿，感謝科研朋友為了生命科學(xué)努力付出，祝愿每一位科研朋友都能享受到科研樂趣，兔抗RRP8多克隆抗體將會(huì)一直和科研工作者一起為科學(xué)研究奉獻(xiàn)綿薄之力。
詳情介紹：


中文名稱：  兔抗RRP8多克隆抗體    

英文名稱： Anti-RRP8 rabbit polyclonal antibody

別      名： ribosomal RNA processing 8; NML; KIAA0409

相關(guān)類別： 一抗

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

抗      原： RRP8

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

Applications:

ELISA, WB, IHC

Name of antibody:

RRP8

Immunogen:

Fusion protein of human RRP8

Full name:

ribosomal RNA processing 8

Synonyms:

NML; KIAA0409

SwissProt:

O43159

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human breast cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

51 kDa

WB Positive control:

Human cerebella tissue, K562 cell lysates

WB Recommended dilution:

500-2000




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