產(chǎn)品中心
產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：兔抗SLAMF7多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫(kù)存：60
  • 產(chǎn)品文檔：
你添加了1件商品 查看購(gòu)物車(chē)
簡(jiǎn)單介紹：
兔抗SLAMF7多克隆抗體公司銷(xiāo)售的產(chǎn)品在消費(fèi)者當(dāng)中享有較高的地位，公司與多家零售商和代理商建立了長(zhǎng)期穩(wěn)定的合作關(guān)系。公司銷(xiāo)售經(jīng)銷(xiāo)的Elisa試劑盒、抗體、、細(xì)胞、血清、等品種齊全、價(jià)格合理。本司銷(xiāo)售實(shí)力雄厚，重信用、守合同、保證產(chǎn)品質(zhì)量，以多品種經(jīng)營(yíng)特色和薄利多銷(xiāo)的原則，贏得了廣大客戶的信任?。。?
詳情介紹：

中文名稱(chēng)：  兔抗SLAMF7多克隆抗體 

英文名稱(chēng)： Anti-SLAMF7 rabbit polyclonal antibody

別      名： SLAM family member 7; 19A; CS1; CD319; CRACC

抗      原： SLAMF7

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

相關(guān)類(lèi)別： 一抗

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (PubMed:23695528).

Applications:

ELISA, IHC

Name of antibody:

SLAMF7

Immunogen:

Fusion protein of human SLAMF7

Full name:

SLAM family member 7

Synonyms:

19A; CS1; CD319; CRACC

SwissProt:

Q9NQ25

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

30-150



姓名：
電話：
您的需求：