中文名稱:兔抗SLC8A1多克隆抗體
英文名稱: Anti-SLC8A1 rabbit polyclonal antibody
別 名: NCX1
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: SLC8A1
相關(guān)類別: 一抗
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
Background: |
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation. |
Applications: |
ELISA, IHC |
Name of antibody: |
SLC8A1 |
Immunogen: |
Synthetic peptide of human SLC8A1 |
Full name: |
solute carrier family 8 (sodium/calcium exchanger), member 1 |
Synonyms: |
NCX1 |
SwissProt: |
P32418 |
ELISA Recommended dilution: |
500-1000 |
IHC positive control: |
Human brain and human tonsil |
IHC Recommend dilution: |
25-100 |