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  • 產(chǎn)品名稱(chēng):兔抗SLFN5多克隆抗體

  • 產(chǎn)品型號(hào):100ul
  • 產(chǎn)品廠(chǎng)商:通蔚生物
  • 產(chǎn)品價(jià)格:1560
  • 產(chǎn)品庫(kù)存:60
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詳情介紹:

中文名稱(chēng):兔抗SLFN5多克隆抗體 

英文名稱(chēng): Anti-SLFN5 rabbit polyclonal antibody

相關(guān)類(lèi)別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: SLFN5

反應(yīng)種屬: Human

標(biāo) 記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Slfn5 (schlafen family member 5) is an 891 amino acid protein that exists as multiple alternatively spliced isoforms and is thought to play a role in hematopoeitic cell differentiation. The gene encoding Slfn5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Applications:

ELISA, IHC

Name of antibody:

SLFN5

Immunogen:

Fusion protein of human SLFN5

Full name:

schlafen family member 5

SwissProt:

Q08AF3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer;

IHC Recommend dilution:

25-100


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