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  • 產(chǎn)品名稱:兔抗SMAD2(Ab465) 多克隆抗體

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詳情介紹:

中文名稱:兔抗SMAD2(Ab-465) 多克隆抗體  

英文名稱: Anti-SMAD2(Ab-465) rabbit polyclonal antibody

別      名: JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

儲(chǔ)      存: 冷凍(-20℃) 避光

抗      原: SMAD2(Ab-465)

宿      主: Rabbit

反應(yīng)種屬: Human

相關(guān)類別: 一抗

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Applications:

WB

Name of antibody:

SMAD2(Ab-465)

Immunogen:

Synthesized peptide derived from C-terminal of human Smad2.

Full name:

SMAD family member 2

Synonyms:

JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

SwissProt:

Q15796

WB Predicted band size:

52 kDa

WB Positive control:

293 cells, JurKat cells, HepG2 cells and K562 cells lysates

WB Recommended dilution:

500-3000


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