中文名稱:兔抗SMAD2(Ab-465) 多克隆抗體
英文名稱: Anti-SMAD2(Ab-465) rabbit polyclonal antibody
別 名: JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2
儲(chǔ) 存: 冷凍(-20℃) 避光
抗 原: SMAD2(Ab-465)
宿 主: Rabbit
反應(yīng)種屬: Human
相關(guān)類別: 一抗
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. |
Applications: |
WB |
Name of antibody: |
SMAD2(Ab-465) |
Immunogen: |
Synthesized peptide derived from C-terminal of human Smad2. |
Full name: |
SMAD family member 2 |
Synonyms: |
JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2 |
SwissProt: |
Q15796 |
WB Predicted band size: |
52 kDa |
WB Positive control: |
293 cells, JurKat cells, HepG2 cells and K562 cells lysates |
WB Recommended dilution: |
500-3000 |