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  • 產(chǎn)品名稱：兔抗SPIN2B多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫(kù)存：60
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
在廣大科研用戶的幫助和支持下，經(jīng)過(guò)不懈的努力，我司兔抗SPIN2B多克隆抗體產(chǎn)品以過(guò)硬的質(zhì)量和服務(wù)態(tài)度，為客戶提供一個(gè)穩(wěn)定平臺(tái)，成為客戶可信賴的長(zhǎng)期合作的伙伴，相信在未來(lái)的工作中，一定能夠成為您得力的實(shí)驗(yàn)科研助手。
詳情介紹：

中文名稱：兔抗SPIN2B多克隆抗體 

英文名稱： Anti-SPIN2B rabbit polyclonal antibody

別      名： SPIN-2; dJ323P24.2; SPIN2_duplicate

抗      原： SPIN2B

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

相關(guān)類別： 一抗

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.

Applications:

ELISA, IHC

Name of antibody:

SPIN2B

Immunogen:

Full length fusion protein

Full name:

Spindlin family, member 2B

Synonyms：

SPIN-2; dJ323P24.2; SPIN2_duplicate

SwissProt:

Q9BPZ2

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

25-100


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