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  • 產(chǎn)品名稱：兔抗SRPK2多克隆抗體

  • 產(chǎn)品型號：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫存：60
  • 產(chǎn)品文檔：
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簡單介紹：
在廣大科研用戶的幫助和支持下，經(jīng)過不懈的努力，我司兔抗SRPK2多克隆抗體 產(chǎn)品以過硬的質(zhì)量和服務(wù)態(tài)度，為客戶提供一個(gè)穩(wěn)定平臺，成為客戶可信賴的長期合作的伙伴，相信在未來的工作中，一定能夠成為您得力的實(shí)驗(yàn)科研助手。
詳情介紹：

中文名稱：兔抗SRPK2多克隆抗體 

英文名稱： Anti-SRPK2 rabbit polyclonal antibody

別      名： SRSF protein kinase 2; SFRSK2

相關(guān)類別： 一抗

儲(chǔ)      存： 冷凍（-20℃）

宿      主： Rabbit

抗      原： SRPK2

反應(yīng)種屬： Human, Mouse

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.

Applications:

ELISA, IHC

Name of antibody:

SRPK2

Immunogen:

Fusion protein of human SRPK2

Full name:

SRSF protein kinase 2

Synonyms:

SFRSK2

SwissProt:

P78362

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

100-300


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