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  • 產(chǎn)品名稱:PTPRK抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:

中文名稱: PTPRK抗原(重組蛋白)


英文名稱: PTPRK Antigen (Recombinant Protein)

別     名:  R-PTP-kappa

儲     存:  冷凍(-20℃)

關(guān)類別: 抗原

概    述

Full length fusion protein

技術(shù)規(guī)格

Full name:

protein tyrosine phosphatase, receptor type, K

Synonyms:

R-PTP-kappa

Swissprot:

Q15262

Gene Accession:

BC063596

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.








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