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  • 產(chǎn)品名稱：SLFN5 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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根據(jù)數(shù)據(jù)統(tǒng)計(jì) SLFN5 抗原（重組蛋白）在同類產(chǎn)品中銷量很好，實(shí)驗(yàn)效果顯著。我司具有明顯的價(jià)格優(yōu)勢(shì)，在保障產(chǎn)品質(zhì)量條件下不斷提升技術(shù)降低成本，使各項(xiàng)指標(biāo)越開越**。可以滿足生物化學(xué)、分子生物學(xué)、細(xì)胞生物學(xué)、免疫學(xué)等生物實(shí)驗(yàn)需求。
詳情介紹：


中文名稱： SLFN5 抗原（重組蛋白）

英文名稱： SLFN5 Antigen (Recombinant Protein)

別     名：  schlafen family member 5

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 139-338 amino acids of human SLFN5

技術(shù)規(guī)格

Full name:

schlafen family member 5

Swissprot:

Q08AF3

Gene Accession:

BC021238

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Slfn5 (schlafen family member 5) is an 891 amino acid protein that exists as multiple alternatively spliced isoforms and is thought to play a role in hematopoeitic cell differentiation. The gene encoding Slfn5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.






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