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  • 產(chǎn)品名稱:SOCS3抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫(kù)存:35
  • 產(chǎn)品文檔:
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詳情介紹:


中文名稱: SOCS3抗原(重組蛋白)

英文名稱: SOCS3 Antigen (Recombinant Protein)

別     名:  CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概    述

Full length fusion protein

技術(shù)規(guī)格

Full name:

suppressor of cytokine signaling 3

Synonyms:

CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3

Swissprot:

O14543

Gene Accession:

BC060858

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.







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