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  • 產(chǎn)品名稱(chēng)：SPIN2B抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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根據(jù)數(shù)據(jù)統(tǒng)計(jì) SPIN2B抗原（重組蛋白）在同類(lèi)產(chǎn)品中銷(xiāo)量很好，實(shí)驗(yàn)效果顯著。我司具有明顯的價(jià)格優(yōu)勢(shì)，在保障產(chǎn)品質(zhì)量條件下不斷提升技術(shù)降低成本，使各項(xiàng)指標(biāo)越開(kāi)越**。可以滿(mǎn)足生物化學(xué)、分子生物學(xué)、細(xì)胞生物學(xué)、免疫學(xué)等生物實(shí)驗(yàn)需求。
詳情介紹：


中文名稱(chēng)： SPIN2B抗原（重組蛋白）

英文名稱(chēng)： SPIN2B Antigen (Recombinant Protein)

別     名：  SPIN-2; dJ323P24.2; SPIN2_duplicate

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

Spindlin family, member 2B

Synonyms:

SPIN-2; dJ323P24.2; SPIN2_duplicate

Swissprot:

Q9BPZ2

Gene Accession:

BC000044

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.






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