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  • 產(chǎn)品名稱:TADA3 抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫存:35
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詳情介紹:

中文名稱: TADA3 抗原(重組蛋白)

英文名稱: TADA3 Antigen (Recombinant Protein)

別     名:  transcriptional adaptor 3; ADA3; NGG1; hADA3; STAF54; TADA3L

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 170-369 amino acids of human TADA3

技術(shù)規(guī)格

Full name:

transcriptional adaptor 3

Synonyms:

ADA3; NGG1; hADA3; STAF54; TADA3L

Swissprot:

O75528

Gene Accession:

BC009240

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.





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