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  • 產(chǎn)品名稱:TYROBP抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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TYROBP抗原(重組蛋白)將進一步加強人才培養(yǎng)、產(chǎn)品**,持續(xù)不斷地提升企業(yè)核心竟爭力,實現(xiàn)具有高科技產(chǎn)業(yè)體系、知識化創(chuàng)業(yè)團隊的國際化企業(yè),更好、更快捷、更全方位的服務(wù)于生命科學(xué)領(lǐng)域,迎接新一輪世界經(jīng)濟一體化所帶來的機遇與挑戰(zhàn)。
詳情介紹:

中文名稱: TYROBP抗原(重組蛋白)

英文名稱: TYROBP Antigen (Recombinant Protein)

別     名:  DAP12; KARAP; PLOSL

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

TYRO protein tyrosine kinase binding protein

Synonyms:

DAP12; KARAP; PLOSL

Swissprot:

O43914

Gene Accession:

BC011175

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.





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