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  • 產(chǎn)品名稱:AMACR抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫存:35
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詳情介紹:



中文名稱: AMACR抗原(重組蛋白)

英文名稱: AMACR Antigen (Recombinant Protein)
 
儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 15-175 amino acids of human AMACR

技術(shù)規(guī)格

Full name:

alpha-methylacyl-CoA racemase

Synonyms:

RM; RACE; CBAS4; AMACRD

Swissprot:

Q9UHK6

Gene Accession:

BC009471

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with *****-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.






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