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  • 產(chǎn)品名稱：BIN1抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
BIN1抗原（重組蛋白）打造了一支訓練有素的技術團隊，為抗體產(chǎn)品質(zhì)量提供了強有力的保障，一直致力于研發(fā)生產(chǎn)高質(zhì)量的科研試劑，為生命科學提供**的蛋白檢測相關產(chǎn)品，先進的實驗設備，強大的技術力量，誠信的服務態(tài)度是您實驗成果的保障！
詳情介紹：


中文名稱： BIN1抗原（重組蛋白）

英文名稱： BIN1 Antigen (Recombinant Protein)

儲     存： 冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to C terminal 250 amino acids of human BIN1

技術規(guī)格

Full name:

bridging integrator 1

Synonyms:

AMPH2; AMPHL; SH3P9

Swissprot:

O00499

Gene Accession:

BC004101

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.





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