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  • 產(chǎn)品名稱：CASP14抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
CASP14抗原（重組蛋白）打造了一支訓(xùn)練有素的技術(shù)團(tuán)隊(duì)，為抗體產(chǎn)品質(zhì)量提供了強(qiáng)有力的保障，一直致力于研發(fā)生產(chǎn)高質(zhì)量的科研試劑，為生命科學(xué)提供**的蛋白檢測相關(guān)產(chǎn)品，先進(jìn)的實(shí)驗(yàn)設(shè)備，強(qiáng)大的技術(shù)力量，誠信的服務(wù)態(tài)度是您實(shí)驗(yàn)成果的保障！
詳情介紹：


中文名稱： CASP14抗原（重組蛋白）

英文名稱： CASP14 Antigen (Recombinant Protein)

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 6-242 amino acids of human CASP14

技術(shù)規(guī)格

Full name:

caspase 14, apoptosis-related cysteine peptidase

Swissprot:

P31944

Gene Accession:

BC069541

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.





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