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  • 產(chǎn)品名稱：CDK4抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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針對(duì)不同行業(yè)的需求，我司不斷完善、更新技術(shù)和方法。CDK4抗原（重組蛋白）在實(shí)驗(yàn)室應(yīng)用的比較廣泛，被業(yè)內(nèi)眾多的科研人士認(rèn)可和推廣。公司以上等，齊全的抗體產(chǎn)品和上等的技術(shù)團(tuán)隊(duì)得到了國家各大實(shí)驗(yàn)高校及科研單位的認(rèn)可和贊譽(yù)，擁有和好的知名度和口碑。
詳情介紹：


中文名稱： CDK4抗原（重組蛋白）

英文名稱： CDK4 Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1-303 amino acids of human CDK4

技術(shù)規(guī)格

Full name:

cyclin dependent kinase 4

Synonyms:

CMM3; PSK-J3

Swissprot:

P11802

Gene Accession:

BC003644

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.





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