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  • 產(chǎn)品名稱:CTNNA1抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:


中文名稱: CTNNA1抗原(重組蛋白)

英文名稱: CTNNA1 Antigen (Recombinant Protein)

     存:  冷凍(-20℃)

關(guān)類別: 抗原

概     

Fusion protein corresponding to C terminal 300 amino acids of human CTNNA1

技術(shù)規(guī)格

Full name:

Catenin (cadherin-associated protein), alpha 1, 102kDa

Synonyms:

CAP102

Swissprot:

P35221

Gene Accession:

BC031262

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.





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