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  • 產(chǎn)品名稱:CUL5抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫(kù)存:35
  • 產(chǎn)品文檔:
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詳情介紹:


中文名稱: CUL5抗原(重組蛋白)

英文名稱: CUL5 Antigen (Recombinant Protein)

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 481-780 amino acids of human CUL5


技術(shù)規(guī)格


Full name:

cullin 5

Synonyms:

CUL-5; VACM1; VACM-1

Swissprot:

Q93034

Gene Accession:

BC063306

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.





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