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  • 產品名稱：DUSP6抗原（重組蛋白）

  • 產品型號：1mg
  • 產品廠商：通蔚生物
  • 產品價格：3580
  • 產品庫存：35
  • 產品文檔：
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我司DUSP6抗原（重組蛋白）是一家集研發(fā)、生產、銷售、服務于一體的國際**生物******，專業(yè)提供抗體、蛋白、Elisa試劑盒、細胞等生物產品，產品種類齊全、質量可靠、價格優(yōu)惠，我司致力于向國內生命科學研究人員提供**的產品和服務。
詳情介紹：


中文名稱： DUSP6抗原（重組蛋白）

英文名稱： DUSP6 Antigen (Recombinant Protein)

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 206-381 amino acids of human DUSP6

技術規(guī)格

Full name:

dual specificity phosphatase 6

Synonyms:

MKP3, PYST1

Swissprot:

Q16828

Gene Accession:

BC005047

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.





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