產(chǎn)品中心
產(chǎn)品詳情

  • 產(chǎn)品名稱：ERG抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
你添加了1件商品 查看購(gòu)物車
簡(jiǎn)單介紹：
我司ERG抗原（重組蛋白）是一家集研發(fā)、生產(chǎn)、銷售、服務(wù)于一體的國(guó)際**生物******，專業(yè)提供抗體、蛋白、Elisa試劑盒、細(xì)胞等生物產(chǎn)品，產(chǎn)品種類齊全、質(zhì)量可靠、價(jià)格優(yōu)惠，我司致力于向國(guó)內(nèi)生命科學(xué)研究人員提供**的產(chǎn)品和服務(wù)。
詳情介紹：


中文名稱： ERG抗原（重組蛋白）

英文名稱： ERG Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from N terminal 150 amino acids of human ERG

技術(shù)規(guī)格

Full name:

v-ets erythroblastosis virus E26 oncogene homolog (avian)

Synonyms:

p55; erg-3

Swissprot:

P11308

Gene Accession:

BC040168

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.





姓名：
電話：
您的需求：