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  • 產(chǎn)品名稱：GCLC 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
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中文名稱： GCLC 抗原（重組蛋白）

英文名稱： GCLC Antigen (Recombinant Protein)

別     名：  glutamate-cysteine ligase, catalytic subunit; GCL; GCS; GLCL; GLCLC

相關(guān)類別： 抗原

儲(chǔ)     存：  冷凍（-20℃） 

概     述

Fusion protein corresponding to N terminal 252 amino acids of human GCLC

技術(shù)規(guī)格

Full name:

glutamate-cysteine ligase, catalytic subunit

Synonyms:

GCL; GCS; GLCL; GLCLC

Swissprot:

P48506

Gene Accession:

BC022487

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.






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