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  • 產(chǎn)品名稱:HP抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:3580
  • 產(chǎn)品庫存:35
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HP抗原(重組蛋白)秉承“全mian、專業(yè)、上等、快捷”的服務理念,協(xié)助推動中國生命科學研究的進步,為了更好更快捷的提供服務,存?zhèn)淞舜罅楷F(xiàn)貨,配合優(yōu)良的銷售隊伍以及專業(yè)的技術支持,隨時為客戶提供*上等的服務,客戶的滿意和信任是我們*大的動力。
詳情介紹:



中文名稱: HP抗原(重組蛋白)

英文名稱: HP Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Fusion protein corresponding to a region derived from 162-406 amino acids of human HP

技術規(guī)格

Full name:

haptoglobin

Synonyms:

BP, HPA1S, HP2ALPHA2

Swissprot:

P00738

Gene Accession:

BC121125

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.






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