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  • 產(chǎn)品名稱：ICOS抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
ICOS抗原（重組蛋白）秉承“全mian、專業(yè)、上等、快捷”的服務(wù)理念，協(xié)助推動中國生命科學(xué)研究的進(jìn)步，為了更好更快捷的提供服務(wù)，存?zhèn)淞舜罅楷F(xiàn)貨，配合優(yōu)良的銷售隊伍以及專業(yè)的技術(shù)支持，隨時為客戶提供*上等的服務(wù)，客戶的滿意和信任是我們*大的動力。
詳情介紹：



中文名稱： ICOS抗原（重組蛋白）

英文名稱： ICOS Antigen (Recombinant Protein)

別     名：  AILIM, CD278, CVID1

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 21-140 amino acids of human ICOS

技術(shù)規(guī)格

Full name:

inducible T-cell co-stimulator

Synonyms:

AILIM, CD278, CVID1

Swissprot:

Q9Y6W8

Gene Accession:

BC028006

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.







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