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  • 產(chǎn)品名稱:IKBIP 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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IKBIP 抗原(重組蛋白)一直視質(zhì)量控制為企業(yè)的生命,追求企業(yè)競爭力的不斷提升,始終秉承信譽為生存之本的宗旨,以過硬的質(zhì)量和優(yōu)良的服務(wù)來維護和拓展市場,*大限度的滿足客戶的需求,與客戶共贏,是我們的發(fā)展目標,愿與您精誠合作,共創(chuàng)美好的未來。
詳情介紹:


中文名稱: IKBIP 抗原(重組蛋白)

英文名稱: IKBIP Antigen (Recombinant Protein)

別     名:  IKBKB interacting protein; IKIP

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 71-350 amino acids of human IKBIP

技術(shù)規(guī)格

Full name:

IKBKB interacting protein

Synonyms:

IKIP

Swissprot:

Q70UQ0

Gene Accession:

BC058933

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.





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