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  • 產(chǎn)品名稱:IL10RA抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
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IL10RA抗原(重組蛋白)一直視質(zhì)量控制為企業(yè)的生命,追求企業(yè)競(jìng)爭(zhēng)力的不斷提升,始終秉承信譽(yù)為生存之本的宗旨,以過硬的質(zhì)量和優(yōu)良的服務(wù)來維護(hù)和拓展市場(chǎng),*大限度的滿足客戶的需求,與客戶共贏,是我們的發(fā)展目標(biāo),愿與您精誠(chéng)合作,共創(chuàng)美好的未來。
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中文名稱:IL10RA抗原(重組蛋白)

英文名稱: IL10RA Antigen (Recombinant Protein)

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to C terminal 329 amino acids of human IL10RA

技術(shù)規(guī)格

Full name:

Interleukin-10 receptor subunit alpha

Synonyms:

CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1

Swissprot:

Q13651

Gene Accession:

BC028082

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.






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