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  • 產品名稱:IL21R抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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詳情介紹:



中文名稱: IL21R抗原(重組蛋白)

英文名稱: IL21R Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Fusion protein corresponding to a region derived from 20-232 amino acids of human IL21R

技術規(guī)格

Full name:

interleukin 21 receptorp

Synonyms:

NILR; CD360

Swissprot:

Q9HBE5

Gene Accession:

BC004348

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.






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