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  • 產(chǎn)品名稱：ITGB3BP抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：



中文名稱： ITGB3BP抗原（重組蛋白）

英文名稱： ITGB3BP Antigen (Recombinant Protein)

別     名：  CENPR, NRIF3, TAP20, CENP-R, HSU37139

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 41-177 amino acids of human ITGB3BP

技術(shù)規(guī)格

Full name:

integrin beta 3 binding protein (beta3-endonexin)

Synonyms:

CENPR, NRIF3, TAP20, CENP-R, HSU37139

Swissprot:

Q13352

Gene Accession:

BC014385

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.





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