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  • 產(chǎn)品名稱:ITGA4抗原(重組蛋白

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
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  • 產(chǎn)品庫(kù)存:35
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中文名稱: ITGA4抗原(重組蛋白)

英文名稱: ITGA4 Antigen (Recombinant Protein)

別     名:  IA4; CD49D
   
儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概     述

Fusion protein corresponding to a region derived from 756-1032 amino acids of human ITGA4

技術(shù)規(guī)格

Full name:

integrin subunit alpha 4

Synonyms:

IA4; CD49D

Swissprot:

P13612

Gene Accession:

BC080190

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.






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