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  • 產(chǎn)品名稱:ITGA2B 抗原(重組蛋白)

  • 產(chǎn)品型號(hào):100ug
  • 產(chǎn)品廠商:通蔚生物
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詳情介紹:


中文名稱: ITGA2B 抗原(重組蛋白)

英文名稱: ITGA2B Antigen (Recombinant Protein)

別     名:  integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; B

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 630-887 amino acids of human ITGA2B

技術(shù)規(guī)格

Full name:

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Synonyms:

GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16

Swissprot:

P08514

Gene Accession:

BC117443

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.





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