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  • 產(chǎn)品名稱：IRF9抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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中文名稱： IRF9抗原（重組蛋白）

英文名稱：  IRF9 Antigen (Recombinant Protein)

別     名：   p48; IRF-9; ISGF3; ISGF3G

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概      述

Fusion protein corresponding to a region derived from 188-393 amino acids of human IRF9

技術(shù)規(guī)格

Full name:

interferon regulatory factor 9

Synonyms:

p48; IRF-9; ISGF3; ISGF3G

Swissprot:

Q00978

Gene Accession:

BC035716

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.







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