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  • 產(chǎn)品名稱：IRF4抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
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詳情介紹：



中文名稱： IRF4抗原（重組蛋白）

英文名稱： IRF4 Antigen (Recombinant Protein)

別     名：  MUM1; LSIRF; SHEP8; NF-EM5

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 129-451 amino acids of human IRF4

技術(shù)規(guī)格

Full name:

interferon regulatory factor 4

Synonyms:

MUM1; LSIRF; SHEP8; NF-EM5

Swissprot:

Q15306

Gene Accession:

BC015752

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.






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