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  • 產品名稱：IQGAP3抗原（重組蛋白

  • 產品型號：1mg
  • 產品廠商：通蔚生物
  • 產品價格：3580
  • 產品庫存：35
  • 產品文檔：
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IQGAP3抗原（重組蛋白）有一支專業(yè)化的銷售和技術服務團隊，成熟化的專業(yè)性配備實驗室，力求售前、售中、售后專業(yè)、快捷、方便、及時，經營原則是質量**，誠信為本，以質量是企業(yè)的生命，誠信是經營的資本為警醒，嚴把所售出商品的質量關。歡迎來電咨詢訂購！
詳情介紹：



中文名稱： IQGAP3抗原（重組蛋白）

英文名稱： IQGAP3 Antigen (Recombinant Protein)

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1165-1325 amino acids of human IQGAP3

技術規(guī)格

Full name:

IQ motif containing GTPase activating protein 3

Swissprot:

Q86VI3

Gene Accession:

BC131536

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.







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